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Corneal Endothelial
Cell Therapy

Two lab workers on either edge of the frame, turned looking at each other and smiling while holding lab equipment in front of a lab bay.

Our initial candidate treats dystrophies that cause corneal blindness.


In Japan, early clinical research1 followed by dose-ranging and confirmatory clinical trials have successfully demonstrated the safety, efficacy, and tolerability of our lead product candidate. We have received regulatory approval from Japan’s PMDA.

In the US, we are preparing to initiate clinical trials, with additional clinical development plans underway in the EU.

Image of a pipeline diagram indicating Japan is in regulatory approval, the US is in between Phase I and Phase II and the EU is in clinical development planning.


  1. Kinoshita S, Koizumi N, Ueno M, et al. Injection of cultured cells with a ROCK inhibitor for bullous keratopathy. N Engl J Med. 2018;378(11):995-1003.

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